Research Project

Project Title:	6-month multicenter, randomized, double-blind, placebo-controlled study to evaluate the efficacy, safety and PK/PD of an age- & body weight-adjusted oral finerenone regimen, in addition to an ACEI/ARB, for the treatment of child. with chronic kidney dis.
Project Type:	Clinical Trial, Enrolment ongoing Adjunct biobank: DNA, Serum, Plasma, Urine
Disease group(s):	Hereditary glomerulopathies, Immune glomerulopathies, Congenital malformations & ciliopathies, Pediatric CKD & dialysis
Project Summary:	A 6-month multicenter, randomized, double-blind, placebo-controlled study to evaluate the efficacy, safety and PK/PD of an age-and body weight-adjusted oral finerenone regimen, in addition to an ACEI or ARB, for the treatment of pediatric patients, 6 months to <18 years of age, with CKD and severely increased proteinuria (UPCR ≥0.50 g/g).
Lead principal investigator(s):	Enrico Verrina, Genoa
Co-investigator(s):	Francesca Lugani, Genoa
Project Period:	03/2022 - 03/2026
Sponsors:	Industry