Research Project

Project Title:	Efficacy and Safety of Iptacopan (LNP023) in Adult Patients With Atypical Hemolytic Uremic Syndrome Naive to Complement Inhibitor Therapy (APPELHUS)
Project Type:	Clinical Trial, Enrolment ongoing
Disease group(s):	Immune glomerulopathies
Project Summary:	The purpose of this Phase 3 study is to determine whether iptacopan (LNP023) is efficacious and safe for the treatment of aHUS in adult patients who are treatment naive to complement inhibitor therapy.
Lead principal investigator(s):	SMARAGDI MARINAKI, Athen
Co-investigator(s):	Stathis Tsiakas, Athens
Project Period:	01/2022 - 01/2026
Sponsors:	Industry
Project web page:	https://www.novartis.com/clinicaltrials/study/nct04889430
ClinicalTrials.gov:	NCT04889430
EudraCT Nr.:	2023-508840-22-00