Project Title: |
Determinants of immunosuppressive dose requirements in children after solid organ transplantation |
Project Type: |
Observational Study, Enrolment ongoing Adjunct biobank: DNA |
Disease group(s): |
Pediatric kidney transplantation |
Project Summary: |
To determine the course and determinants of individual immunosuppressive dose requirements and their side effects in children during long-term follow up after solid organ transplantation. Study design: Prospective single-centre study (University Hospitals Leuven) at the department of pediatric solid organ transplantation collecting patient/laboratory/ pharmacokinetic data (obtained during routine clinical care) in combination with pharmacogenetic analysis of recipient and donor |
Lead principal investigator(s): |
Noel Knops, Leuven |
Co-investigator(s): |
Elena Levtchenko, Amsterdam |
Project Period: |
04/2013 - 12/2021 |
Sponsors: |
Local resources |
ClinicalTrials.gov: |
NCT01767350 |