Research Project

Project Title:

LEARNS: Levamisole as Adjuvant therapy to Reduce relapses of Nephrotic Syndrome

Project Type:

Clinical Trial, Enrolment ongoing
Adjunct biobank: Serum, Urine

Disease group(s):

Immune glomerulopathies

Project Summary:

The LEARNS study evaluates the effect of a combination therapy with prednisolone and levamisole on the prevention of relapses in children with first episode of steroid-sensitive nephrotic syndrome. Furthermore, the LEARNS study investigates pharmacokinetics and pharmacodynamics of prednisolone and levamisole, Health-Related-Quality-of-Life, Immunomics in children with first episode of SSNS.

Lead principal investigator(s):

Antonia Bouts, Amsterdam

Co-investigator(s):

Sandrine Florquin, Amsterdam
Floor Veltkamp, Amsterdam
Djera Khan, Amsterdam
Jeroen Guikema, Amsterdam
Michiel Schreuder, Nijmegen

Project Period:

05/2018   -   01/2028

Sponsors:

Non-profit foundation, National funding agency

Project web page:

www.learns.nl

EudraCT Nr.:

2017-001025-41

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