Thematic Area: 
Autosomal Dominant Polycystic Kidney Disease   

KDIGO 2025 Clinical Practice Guideline for the Evaluation, Management, and Treatment of Autosomal Dominant Polycystic Kidney Disease (ADPKD)

Reference: Kidney Disease: Improving Global Outcomes (KDIGO) ADPKD Work Group. KDIGO 2025 Clinical Practice Guideline for the Evaluation, Management, and Treatment of Autosomal Dominant Polycystic Kidney Disease (ADPKD). Kidney Int. 2025;107(2S):S1–S239

KDIGO 2025 clinical practice guideline for the evaluation, management, and treatment of autosomal dominant polycystic kidney disease (ADPKD): executive summary

Reference: Torres VE, Ahn C, Barten TRM, et al. KDIGO 2025 clinical practice guideline for the evaluation, management, and treatment of autosomal dominant polycystic kidney disease (ADPKD): executive summary. Kidney Int. 2025;107(2):234-254. doi:10.1016/j.kint.2024.07.010

The KDIGO 2025 Clinical Practice Guideline (CPG) on ADPKD was reviewed and evaluated by ERKNet experts using the AGREE-II methodology. Following this assessment, the ERKNet Network Board officially endorsed the guideline and committed to implementing its recommendations in clinical practice.

An update on the use of tolvaptan for autosomal dominant polycystic kidney disease: consensus statement on behalf of the ERA Working Group on Inherited Kidney Disorders, the European Rare Kidney Disease Reference Network and Polycystic Kidney Disease International

Reference: Müller RU, Messchendorp AL, Birn H, et al. Nephrol Dial Transplant. (2022). doi: 10.1093/ndt/gfab312

Collaboration: ERKNet, ERA, Polycystic Kidney Disease International

International consensus statement on the diagnosis and management of autosomal dominant polycystic kidney disease in children and young people

Reference: Gimpel C, Bergmann C, Bockenhauer D, et al. Nat Rev Nephrol. (2019). doi: 10.1038/s41581-019-0155-2

Autosomal Dominant Polycystic Kidney Disease (ADPKD): Executive Summary from a Kidney Disease: Improving Global Outcomes (KDIGO) Controversies Conference

Reference: Chapman AB, Devuyst O, Eckardt KU, et al. Kidney Int. (2015). doi: 10.1038/ki.2015.59