Birutė Burnytė qualified as a medical doctor at the Faculty of Medicine, Vilnius University, in 2007. From 2008 to 2012, she completed a residency in clinical genetics while working as a junior researcher at the Department of Human and Medical Genetics, Faculty of Medicine, Vilnius University. In 2012, she joined the Center for Medical Genetics at Vilnius University Hospital Santaros Klinikos, where she developed a strong interest in rare diseases. 

From 2014 to 2018, she pursued her PhD studies at Vilnius University. Since 2018, she has worked as an assistant at the Department of Human and Medical Genetics, and since 2022, she has held the position of Associate Professor.

She has published extensively, including in high-impact journals, and continuously enhances her expertise through participation in local and international conferences, congresses, and research projects, contributing significantly to interdisciplinary research.

Her research interests include the etiology and mechanisms of rare diseases, as well as understanding how different genetic backgrounds influence variable phenotypic outcomes in rare genetic disorders. She is the co-author of a substantial number of publications in the field of clinical genetics.

Birutė Burnytė is a member of the Lithuanian Society of Human Genetics, where she has been elected as a General Secretary for the 2016–2021 term and re-elected for the 2021–2026 term. She is also a member of the European Society of Human Genetics (ESHG) and the American Society of Human Genetics (ASHG).